Production & Manufacturing

Choosing a gene expression system is one of the earliest and most consequential manufacturing decisions a biotech founder will make yet it is often made without fully understanding what is at stake. This article breaks down the key expression platforms used in biologic drug development, what differentiates them technically and commercially, and why the choice you make now will follow your program all the way to the clinic and beyond.

AbbVie has outlined plans to build a major new manufacturing facility in Durham, committing $1.4 billion to what will become its largest single-campus capital investment to date. The project, spread across 185 acres, is expected to generate more than...

AbbVie has entered into a global licensing agreement with China-based Haisco Pharmaceutical valued at up to $715 million, aiming to strengthen its presence in pain therapeutics. The Haisco deal grants AbbVie exclusive rights to develop, manufacture, and commercialize multiple...

Danish pharmaceutical major Novo Nordisk has entered into a strategic collaboration with OpenAI to embed artificial intelligence across its drug development operations, with the stated goal of accelerating the delivery of new treatments. Announced on Tuesday, the initiative is...

The deployment of intelligent sensing technology is fundamentally reshaping how pharmaceutical manufacturers manage complex production environments. By providing granular, real-time data at critical control points, these advanced instruments allow for instantaneous process adjustments, ensuring that every batch meets the most rigorous standards of quality and safety.

The evolution of filtration technology is playing a critical role in enhancing the safety and efficiency of pharmaceutical manufacturing. Next-generation filtration systems—featuring advanced membrane materials, automated integrity testing, and single-use designs—provide superior contamination control and operational agility, ensuring that modern drug products meet the most stringent sterility and purity requirements.

The integration of real-time data analytics is revolutionizing the management of pharmaceutical utility systems, providing facility managers with actionable insights into the performance of critical infrastructure. By transforming raw sensor data into meaningful intelligence, manufacturers can optimize energy use, prevent equipment failures, and ensure that utilities like HVAC and water always operate within validated parameters for high-quality drug production.