Leading UK contract development and manufacturing organisation (CDMO) Upperton Pharma Solutions (Upperton) has expanded its oral dosage form capabilities at its newly built headquarters in Nottingham, UK.
Part of Uppertonโs ยฃ15m investment program announced in January this year, the state-of-the-art facility has benefited from a significant investment in large, commercial scale equipment offering powder blending up to 250kg per batch, capsule filling up to 40,000 capsules/hour, dry granulation processing up to 100kg/hour and tablet pressing up to 120,000 tablets/hour.
The expanded capabilities will enable Upperton to continue to meet the growing demand for its oral, nasal and pulmonary dosage form development and GMP manufacturing services, as well as increase its ability to support larger scale, later stage development.
The new equipment is currently being installed and commissioned in a dedicated 700 sq. ft. cleanroom which is one of 10 GMP suites housed in Uppertonโs 50,000 sq.ft. facility expected to be fully operational by the end of 2023.
Upperton CEO Nikki Whitfield said: โThis investment is a pivotal next step as we move towards the completion of our new facility. It will enable us to extend our support for our clientsโ manufacturing needs from early development phases through to Phase III clinical trials, registration batches and subsequent commercial manufacture, all at one, single site.โ
Uppertonโs new ยฃ15m, 50,000 sq. ft. facility in Nottingham has been designed to handle highly potent molecules and controlled drugs, and will allow a significant increase in research and development laboratory space alongside a 10-fold increase in GMP manufacturing space.
Whitfield added: โWe are delighted with the progress we have made. The investment allows us to increase our current development and manufacturing capacity as well as expand our solid dose and spray drying offerings to address the growing needs of our customers.
โWe will also be able to support existing and new clients further in their product development journey, ensuring a consistent and streamlined pathway to approval from product development through to late stage and commercial.


















