Clinical Trials
Neurocrine starts tardive dyskinesia drug Phase II trial
US based Neurocrine Biosciences has started a second double-blind, placebo controlled, randomized cross-over Phase II trial to evaluate NBI- 98854. The company is developing NBI-98854 to address the unmet medical needs of patients suffering...
Clinical Trials
Bionor Pharma to initiate HIV Vacc-4x combination trial
Bionor Pharma is set to initiate a double blinded, randomized and placebo-controlled trial to evaluate HIV-vaccine candidate Vacc-4x in combination with Revlimid.Revlimid is indicated as a treatment for multiple myeloma and anemia due to myelodysplastic syndrome linked with a...
Clinical Trials
Scancell updates on cancer vaccine Phase I clinical trial
The Cohort Review Committee has approved Scancell to further escalate cancer vaccine SCIB1 dose to 4mg from the current 2mg in the Phase I clinical trial and recruitment of the final group of patients as planned. ...
Clinical Trials
Aeras, OETC commence TB drug Phase IIb trial
Aeras and the Oxford-Emergent Tuberculosis Consortium (OETC) have commenced a Phase IIb trial to investigate a new experimental tuberculosis vaccine in TB patients with human immunodeficiency virus (HIV) infection. The trial will evaluate the HIV patients...
Clinical Trials
Alnylam concludes liver cancer drug Phase I trial
US based drug developer Alnylam Pharmaceuticals has concluded an open label, multi-center, dose escalation Phase I trial evaluating ALN-VSP as a treatment for advanced solid tumors with liver involvement. ALN-VSP is a systemically delivered RNAi therapeutic...
Clinical Trials
Sinapis Pharma concludes Phase I stroke drug trial
Sinapis Pharma has concluded first Phase I clinical trial of oral and IV administration of methamphetamine HCl for the treatment of stroke and traumatic brain injury. The single-center, open-label, randomized, two-period, two-treatment, two-sequence, single dose, crossover...
Clinical Trials
Phase 3 Study of YERVOY Metastatic Melanoma Meets Primary Endpoint of Overall Survival
Bristol-Myers Squibb Company announced results from a second Phase 3 randomized, double blind study demonstrating that YERVOY™ (ipilimumab) prolonged the lives of patients with metastatic melanoma. The data were published today in the New England Journal of Medicine and...
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