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Clinical Trials

Medigene strengthens its patent portfolio with a European patent covering T cell identification method

Medigene AG , a clinical stage immune-oncology company focusing on the development of T cell immuno-therapies for the treatment of cancer, announces the grant of European patent EP2327763, a member of Medigene's core patent family concerning the company's allo-restricted...

Aimmune’s peanut succeeds at phase||| trials

U.S. drug developer Aimmune Therapeutics said on Tuesday its peanut allergy drug met the main goal of an eagerly awaited late-stage study, sending its shares up 18 percent premarket. The positive trial data comes nearly four...

AbbVie’s elagolix on a great roll in its PH3 trials

Clinical response was defined as menstrual blood loss volume of less than 80 mL during month six and a 50 percent or greater reduction in menstrual blood loss volume from baseline to month six. The study also met all...

Medigene receives approvals for its first clinical trial with TCR therapy MDG1011

Medigene AG announced that the German Senior Federal Authority "Paul-Ehrlich-Institute" (PEI) and the relevant ethics committee have approved the study design of the first planned Phase I/II clinical trial with its T cell receptor (TCR)-modified T cell therapy MDG1011....

Vertex announces positive results of phase 2 study of Nav1.8 inhibitor VX -150 for Acute pain

Vertex Pharmaceuticals Inc announced positive results of a Phase 2 study of the NaV1.8 inhibitor VX-150 in patients with acute pain following bunionectomy surgery. Treatment with VX-150 showed statistically significant relief of acute pain compared to...

OTEZLA® (Apremilast) Phase II Data Showed Clinically significant Improvements in Patients with Active Ulcerative Colitis

Celgene Corporation announced that data from a randomized, placebo-controlled, multi-center, phase II clinical trial of apremilast in patients with active ulcerative colitis who had failed at least one conventional therapy but were naïve to biologic therapy were presented in...

OTEZLA (Apremilast) Phase III Data Showed good results among Patients with Active Behçet’s Disease with Oral Ulcers

Celgene Corporation announced that data from the phase III RELIEF™ clinical trial of OTEZLA® (apremilast) in patients with active Behçet's Disease with oral ulcers were presented in a late-breaking oral presentation at the 2018 American Academy of Dermatology (AAD)...

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