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Structure and conformational dynamics of fluorine-containing drugs – new insights for small molecule development using 19F NMR spectrometry

Introduction 19F NMR spectrometry is firmly established as a powerful and highly attractive tool in most pharma analytical labs. In this article we summarize the information the technique provides to small molecule drug development scientists and introduce new 19F NMR...

How modern analytical instruments and intelligent software are accelerating metabolite identification in drug discovery and development

Intelligent technologies are transforming the pharmaceutical industry at a company and sector level, where tools such as artificial intelligence, machine learning and blockchain are pushing the limits of data analysis and accelerating decision-making. Meanwhile, similar technological progress is also...

The increase in global demand for in vitro performance testing models for topical products

The most common way to deliver a drug is systemically via an oral tablet or injection. In many cases, delivery of a drug via these routes may not be possible (poor bioavailability) or desirable (due to side effects); In...

The growing world of pharmaceutical supply chain

Pharma and Air Cargo- A match climbing-up the ladder One of the most important developments that took place ever in the invention space was indeed the advent of air cargo. Due to this, the economies came closer and so did...

Calcium: A key nutrient for healthy bones

With an increasingly ageing global population, maintaining bone health for as long as possible is becoming a critical issue. This opens up excellent prospects for calcium supplements. Calcium is one of the most abundant minerals in the body. Healthy bones...

Preventing excursions in controlled lanes

Moving temperature-sensitive pharmaceuticals through controlled cold chain shipping lanes is fraught with challenges. Do the specialist packaging companies have everything covered? Clive Bryant, Global Product and Marketing Director of Softbox Systems, looks at how excursions can be prevented. In many...

A day devoted to driving out botanical adulteration

As demand for botanical ingredients increases year on year, so, too, do the risks of over harvesting. High demand may also persuade dishonest ingredient suppliers to use cheap botanical materials as substitutes for expensive or difficult to grow species....

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