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Researchers block pathway to cancer cell replication

Research suggests that patients with leukemia sometimes relapse because standard chemotherapy fails to kill the self-renewing leukemia initiating cells, often referred to as cancer stem cells. In such cancers, the cells lie dormant for a...

Bristol-Myers Squibb and AstraZeneca expand diabetes alliance

Bristol-Myers Squibb Company and Amylin Pharmaceuticals, Inc. announced that Bristol-Myers Squibb will acquire Amylin for $31.00 per share in cash, pursuant to a cash tender offer and second step merger, or an aggregate purchase price of approximately $5.3...

FDA grants priority review to the new drug application for Bayer’s Regorafenib

Bayer HealthCare announced that the U.S. Food and Drug Administration (FDA) has granted priority review to the New Drug Application (NDA) filed end of April 2012 for the oral multi-kinase inhibitor regorafenib for the treatment of patients with...

New compound holds promise for treating Duchenne MD

Scientists at UCLA have identified a new compound that could treat certain types of genetic disorders in muscles. It is a big first step in what they hope will lead to human clinical trials for Duchenne muscular dystrophy....

Roche to streamline research and development activities

Roche site in Nutley to be closed - respective R&D activities to be consolidated in Switzerland and Germany. The planned site consolidation and the streamlining of research activities within Roche's Pharma Research and Early Development unit to support...

Metformin may lower cancer risk in people with Type 2 diabetes

A commonly prescribed diabetes drug, metformin, reduces the overall cancer risk in people with Type 2 diabetes, a large systematic review study finds. The results have been presented at The Endocrine Society's 94th Annual Meeting in Houston. ...

People with HER2-positive metastatic breast cancer lived longer with Roche’s Perjeta

Roche announced that people with HER-2 positive metastatic breast cancer (mBC) lived significantly longer (overall survival) when treated with the combination of PerjetaTM (pertuzumab), Herceptin® (trastuzumab) and docetaxel chemotherapy, compared to Herceptin and docetaxel chemotherapy alone in the...

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