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Novartis study of Afinitor® in advanced liver cancer does not meet primary endpoint of overall survival
Novartis has announced that results of a global Phase III study showed that Afinitor® (everolimus) did not extend overall survival compared to placebo in patients with locally advanced or metastatic hepatocellular carcinoma (HCC) after progression on or intolerance to...
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Scientists discover potential new way to treat anxiety
Chemically modified inhibitors of the COX-2 enzyme relieve anxiety behaviors in mice by activating natural "endocannabinoids" without gastrointestinal side effects, Vanderbilt University scientists will report next week. Endocannabinoids are natural signaling molecules that activate cannabinoid receptors in the brain,...
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GSK adds to its commitment to GAVI Alliance to help protect millions more children against infectious diseases
GlaxoSmithKline (GSK) has increased its commitment to the GAVI Alliance to provide vaccines to developing countries, helping to protect millions more children against infectious diseases. Under this new agreement, GSK will provide an additional 240...
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Researchers target HER1 receptor for peptide cancer vaccine, therapeutic agents
Small proteins called peptides that consist of 10 to 50 amino acids are being studied as cancer vaccines and as possibly safer, more effective and less costly alternatives to the monoclonal-antibody-based drugs and small-molecule inhibitors now used to treat...
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Studies suggest new key to ‘switching off’ hypertension
A team of University of California, San Diego researchers has designed new compounds that mimic those naturally used by the body to regulate blood pressure. The most promising of them may literally be the key to controlling hypertension, switching...
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New plan of attack in cancer fight
New research conducted by Harvard scientists is laying out a road map to one of the holy grails of modern medicine: a cure for cancer. As described in a paper recently published in eLife, Martin...
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Uncovering a healthier remedy for chronic pain
Physicians and patients who are wary of addiction to pain medication and opioids may soon have a healthier and more natural alternative. A Duke University study revealed that a derivative of DHA (docosahexaenoic acid), a...
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