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Arena begins Phase Ib trial of APD334 to treat autoimmune diseases

US-based Arena Pharmaceuticals has started dosing patients in an investigational Phase Ib clinical trial of APD334, an oral drug candidate that targets the sphingosine 1-phosphate subtype 1 (S1P1) receptor, to treat a number of autoimmune diseases. ...

KIP THE HUMANS: DRUG DISCOVERY BY SIMULATING CELLS

The future of medicine, we're often told, will be personalized. We'll have gene therapies, wearables to monitor our vital signs—maybe even new kinds of vital signs—and robot doctors to diagnose our illnesses. But the real promise...

AstraZeneca’s Bydureon achieves better glycaemic control than insulin glargine in type 2 diabetes

UK-based AstraZeneca has reported results from its longest, randomised, head-to-head DURATION-3 trial of exenatide once-weekly, a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist used to treat type 2 diabetes in adult patients uncontrolled on oral antidiabetic drugs. ...

Boston Therapeutics begins Phase IIb Sugardown trial for type 2 diabetes patients

US-based Boston Therapeutics (BTI) has started a Phase IIb clinical trial SD-002 to evaluate the efficacy and safety of Sugardown in patients with type 2 diabetes taking metformin. Accumed Research Associates is conducting the 24-patient five-week,...

VA’S CONVOLUTED PATIENT SCHEDULING STARTS WITH A ‘HELPLINE’ CALL

Veterans trying to schedule medical appointments in the Veterans Affairs Department’s Phoenix Health Care System entered a Kafkaesque world where they had to call a “helpline” to provide demographic information to an official who would type the data into...

UF Health successfully implements genomic medicine program

GAINESVILLE, Fla. — At the conclusion of the first year of UF Health’s Personalized Medicine Program, the results are in: The program has successfully implemented a process for genetic testing that helps cardiologists identify which patients may benefit from...

GSK and MMV initiate Phase III programme for development of malaria drug

GlaxoSmithKline (GSK) and Medicines for Malaria Venture (MMV) have initiated a Phase III global programme to assess the efficacy and safety of tafenoquine, an investigational medicine, being developed for the treatment and relapse prevention (radical cure) of Plasmodium vivax...

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