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Compound stimulates tumor-fighting protein in cancer therapy

A compound that stimulates the production of a tumor-fighting protein may improve the usefulness of the protein in cancer therapy, according to a team...

Fighting fat with fat: Stem cell discovery identifies potential obesity treatment

Ottawa scientists have discovered a trigger that turns muscle stem cells into brown fat, a form of good fat that could play a critical...

Low vitamin D levels may increase risk of Type 1 diabetes

Having adequate levels of vitamin D during young adulthood may reduce the risk of adult-onset type 1 diabetes by as much as 50%, according...

Shire Reaches Agreement in Principle With U.S. Government

Shire plc , today announced that it has reached an agreement in principle to resolve the previously disclosed civil investigation into Shire's U.S. sales...

GSK response to news article in The Guardian on UK legal proceedings related to Avandia

Responding to a news article in The Guardian on UK legal proceedings related to our type 2 diabetes medicine Avandia (rosiglitazone), we would like...

Discrepant analyses of industry-sponsored clinical trials

Internal pharmaceutical company documents detailing the planned and completed analyses for clinical trials do not always match the publically available report of the completed...

Clinical trials with nonblinded outcome assessors have high observer bias

A new study of randomized clinical trials found significant observer bias toward a more beneficial treatment effect in nonblinded trials when the researcher knew...

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