In the largest and longest head-to-head comparison of two anti-clotting medications, warfarin and aspirin were similar in preventing deaths and strokes in heart failure patients with normal heart rhythm, according to late-breaking research presented at the American Stroke Association's International Stroke Conference 2012.

A new class of nanoparticles, synthesized by a UC Davis research team to prevent premature drug release, holds promise for greater accuracy and effectiveness in delivering cancer drugs to tumors. The work is published in the current issue of Angewandte Chemie, a leading international chemistry journal. 

Mylan Institutional business has launched Levetiracetam in Sodium Chloride Injection of multiple strengths, 500mg/100ml, 1000mg/100ml and 1500mg/100ml, for intravenous use.

Vidacare's study to compare Intraosseous (IO) vascular access to infuse chilled saline as effectively as peripheral intravenous (IV) access to achieve therapeutic hypothermia showed no statistical difference between the two routes.

Drs. Amit Oza of the Princess Margaret Cancer Program, University Health Network and Timothy Perren, St James's Institute of Oncology, Leeds, UK, show the results of an international clinical trial, Treating ovarian cancer with the drug bevacizumab ("Avastin") delays the disease and may also improve survival.

Bayer HealthCare announced that researchers have presented data from two international long-term follow-up studies in multiple sclerosis: the BENEFIT (BEtaferon in Newly Emerging multiple sclerosis For Initial Treatment) 8-Year Extension Study and the Betaferon® 21-Year Long-term Follow-up (LTF) Study. The abstracts were presented at the Fifth Triennial Meeting of the European and American Committees for Treatment and Research in Multiple Sclerosis (ECTRIMS - ACTRIMS) in Amsterdam, The Netherlands.

Shire plc, the global specialty biopharmaceutical company, today presented positive top line results of the first European phase III study of once-daily lisdexamfetamine dimesylate (LDX) in children and adolescents aged 6 to 17 years with Attention-Deficit/Hyperactivity Disorder (ADHD)1.  LDX is the first chemically formulated long-acting, prodrug of dexamfetamine for treatment of ADHD, and is currently licensed only in the US, Canada and Brazil.

An anti-HIV drug also discovered to stop the spread of the genital herpes virus does so by disabling a key DNA enzyme of the herpes virus, according to findings by researchers at the National Institutes of Health and other institutions.

Eli Lilly and Company announced that a pivotal Phase III study of Cialis® (tadalafil) tablets 5 mg for once daily use met its co-primary endpoints, significantly improving measures of both erectile dysfunction (ED) and signs and symptoms of benign prostatic hyperplasia (BPH) in men with both conditions. The study is available online in The Journal of Sexual Medicine. It is one of three efficacy and safety studies included in the supplemental new drug application Lilly submitted to the U.S. Food and Drug Administration (FDA) last year seeking approval for Cialis in the treatment of the signs and symptoms of BPH and the treatment of both ED and the signs and symptoms of BPH (ED+BPH).

Hybrigenics (ALHYG), a bio-pharmaceutical company listed on Alternext in Paris, with a focus on research and development of new treatments of proliferative diseases, announces today the online publication of a scientific article by Dr Ryoko Okamoto and co-authors in the peer-reviewed International Journal of Cancer*. Their preclinical results demonstrate the potential of inecalcitol to inhibit the proliferation of human cancer cells in vitro, as well as the growth of hormone-dependent prostate cancer xenografts in vivo in mice. Dr Okamoto works in Prof Phillip Koeffler's Division of Hematology and Oncology at the Cedars-Sinai Medical Center of the UCLA School of Medicine.