Close
CDMO Safety Testing 2026
Novotech

RCPE and InSilicoTrials to Digitalize and Accelerate the Development of Pharmaceutical Manufacturing Processes

Note* - All images used are for editorial and illustrative purposes only and may not originate from the original news provider or associated company.

Subscribe

- Never miss a story with notifications

- Gain full access to our premium content

- Browse free from any location or device.

Media Packs

Expand Your Reach With Our Customized Solutions Empowering Your Campaigns To Maximize Your Reach & Drive Real Results!

โ€“ Access the Media Pack Now

โ€“ Book a Conference Call

โ€“ Leave Message for Us to Get Back

Related stories

Bristol Myers Squibb Integrates AI to Advance Manufacturing Quality Systems

Bristol Myers Squibb has entered into a strategic agreement...

eschbach Unveils Seqonis Intelligent Operations Platform

eschbach has renamed its flagship enterprise software platform, Shiftconnector,...

Bioprocess Analytics Improving Biologics Manufacturing

The immense complexity of modern biopharmaceutical production is being navigated through the strategic and systematic application of bioprocess analytics improving biologics manufacturing. By leveraging real-time data streams and advanced monitoring tools, manufacturers can gain a granular, molecular-level understanding of cellular behavior and the surrounding environmental conditions within the bioreactor. This proactive, data-driven approach allows for immediate, automated adjustments that optimize therapeutic yield, ensure absolute product consistency, and significantly streamline the arduous path toward commercial-scale production in a highly regulated global environment.
- Advertisement -

RCPE and InSilicoTrials have agreed to an exclusive partnership to commercialize the XPS simulation software. Specifically developed for pharmaceutical applications, XPS allows companies to assess their process configurations in unprecedented detail and explore the decision space without time- and labor-intensive experiments.

The Research Center Pharmaceutical Engineering (RCPE) and InSilicoTrials announced the expansion of their partnership to accel- erate the development of pharmaceutical manufacturing processes by leveraging high-performance modeling and simulation. The ap- proach enables organizations to innovate and optimize their process configurations without additional investments in technical infra- structure and significantly accelerates time-to-value when develop- ing new drug products. RCPEโ€™s proprietary simulation will be offered as a standalone desktop application and integrated into InSilicoTrialsโ€™ market-leading cloud-based platform.

โ€œWeโ€™re honored to have found the perfect partner in InSilicoTrial,โ€ said Prof. Dr. Johannes Khinast, Scientific Director of RCPE. โ€œWith todayโ€˜s announcement, RCPE and InSilicoTrials are combining their expertise to help engineers and researchers make data-driven decisions and deliver new levels of innovation. InSilicoTrialsโ€˜ comprehensive simula- tion platform combined with XPS creates a single-source repository for pharmaceutical development from discovery to dosage form.โ€

โ€œWe are honored to have started this collaboration agreement with such a high-value technologically advanced partner,โ€ said Luca Emili, CEO of InSilicoTrials. โ€œThis step confirms the validity of our business model centered on the integration of computational simulations from the best research centers worldwide. With XPS, InSilicoTrials adds an important model to its platform, further enhancing its contribution to drug development and data-driven decision making.โ€

Dr. Thomas Klein, Business Director of RCPE, added: โ€œIt is exciting to see our technology ready for commercialization and be able to provide the software to customers worldwide. Our multidisciplinary team has demonstrated how our computational models can be used to create better quality products and more efficient processes. This collaboration and our shared developmental efforts truly set the gold standard for modeling and simulation in life sciences.โ€

About XPS

XPS was developed at the RCPE in Graz, Austria. It allows an accurate and ultra-fast calculation of mixing processes for powdery media to an extent that was inconceivable until recently. XPS allows simulat- ing up to 100 million (!) particles simultaneously and with appealing computing speeds. Thus, processes can be described in great detail that reality and simulation seem to merge.

With its unique program architecture, XPS uses the CPU and GPU to depict the behavior and transport of more than 100 million parti- cles without additional computation time. Other standard tools reach their limits at a fraction of that amount. Therefore, the utilization of XPS leads to minimizing the implications of a trial & error approach. XPS is a novel, cross-sector simulation tool for particle-based pro- cesses in process engineering. It can be used for product and equip- ment development or optimization in various fields (Pharma, Food, Equipment manufacture, etc.). Particle-based process steps occur in about 80% of all chemical processes. The simulation of particle flows has been very complex and hardly possible so far.

Never miss a pharmaceutical headline

The pharmaceutical industry moves fast โ€“ stay on top of it with our must - read briefings.

  • The top pharma and life sciences stories, straight to your inbox
  • The biggest news, features, interviews, and analysis
  • Dedicated coverage of the key developments driving the global pharmaceutical sector

Latest stories

Related stories

Bristol Myers Squibb Integrates AI to Advance Manufacturing Quality Systems

Bristol Myers Squibb has entered into a strategic agreement...

eschbach Unveils Seqonis Intelligent Operations Platform

eschbach has renamed its flagship enterprise software platform, Shiftconnector,...

Bioprocess Analytics Improving Biologics Manufacturing

The immense complexity of modern biopharmaceutical production is being navigated through the strategic and systematic application of bioprocess analytics improving biologics manufacturing. By leveraging real-time data streams and advanced monitoring tools, manufacturers can gain a granular, molecular-level understanding of cellular behavior and the surrounding environmental conditions within the bioreactor. This proactive, data-driven approach allows for immediate, automated adjustments that optimize therapeutic yield, ensure absolute product consistency, and significantly streamline the arduous path toward commercial-scale production in a highly regulated global environment.

Cell and Gene Therapy Manufacturing Entering GMP Era

The rapid and profound maturation of the global biopharmaceutical sector is being clearly marked by cell and gene therapy manufacturing entering GMP era. This critical transition involves the large-scale implementation of rigorous and uncompromising Good Manufacturing Practice standards to ensure that these complex, "living" treatments are produced with a level of consistent quality and safety that meets international requirements. By adopting highly automated systems, closed-loop processing, and robust, data-driven regulatory frameworks, the industry is successfully overcoming the historical hurdles of scalability and biological variability, paving the way for these advanced therapies to reach much broader patient populations across the globe.

Subscribe

- Never miss a story with notifications

- Gain full access to our premium content

- Browse free from any location or device.

Media Packs

Expand Your Reach With Our Customized Solutions Empowering Your Campaigns To Maximize Your Reach & Drive Real Results!

โ€“ Access theMedia Pack Now

โ€“ Book a Conference Call

โ€“ Leave Message for Us to Get Back

Translate ยป