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Biomarker predicts response to cancer treatment

VIB researcher Diether Lambrechts, associated with KU Leuven, has discovered a biomarker that might potentially predict which patients will benefit more from treatment with bevacizumab (Avastin). If validated, this discovery could be an important step towards personalized medicine...

FDA approves generic versions of blood thinner Plavix

The U.S. Food and Drug Administration approved generic versions of the blood thinning drug Plavix, which helps reduce the risk of heart attack and stroke by making it less likely that platelets in the blood will clump and...

Amgen’s BiTE® antibody blinatumomab achieved high rate of complete response

Amgen announced updated results from a Phase 2 study that showed treatment with blinatumomab (AMG 103) helped achieve a high-rate of complete response (CR) in 72 percent of adult patients with relapsed or refractory B-precursor acute lymphoblastic leukemia...

In drug-approval race, US FDA ahead of Canada, Europe

The U.S. Food and Drug Administration (FDA) generally approves drug therapies faster and earlier than its counterparts in Canada and Europe, according to a new study by Yale School of Medicine researchers. The study counters perceptions that the...

Bristol-Myers Squibb Foundation Announces $15 Million Expansion of Together on Diabetes® to China and India

The Bristol-Myers Squibb Foundation today announced the expansion of its Together on Diabetes® initiative to China and India, pledging $15 million over five years to help these developing nations with rapidly growing numbers of type 2 diabetes patients....

Serious safety concerns around unlicensed ocular bevacizumab use versus Lucentis

  Recently announced results from two-year CATT (Comparison of Age-related macular degeneration Treatment Trials) adds to the growing body of evidence, including CATT 1-year data and two retrospective database analyses, suggesting serious safety concerns associated with the use of...

AstraZeneca to acquire Ardea Biosciences for $1 billion

AstraZeneca and Ardea Biosciences, Inc. have entered into a definitive merger agreement, pursuant to which AstraZeneca will acquire Ardea, a San Diego, California-based biotechnology company focused on the development of small-molecule therapeutics. Ardea's clinically most advanced product candidate, lesinurad...

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