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Hyphens Pharma to develop and commercialise ByfavoR procedural sedation drug in Singapore

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SGX-Catalist listed Hyphens Pharma International Limited, Singaporeโ€™s leading specialty pharmaceutical and consumer healthcare group, has just announced that its subsidiary, Hyphens Pharma Pte. Ltd., has signed an exclusive sub-license and supply agreement with Hana Pharm Co., Ltd. to develop and commercialise Byfavoยฎ 20mg (remimazolam besylate 20mg) in Singapore.

Byfavoยฎ is an ultra-short-acting intravenous benzodiazepine anaesthetic drug that is used to induce and maintain sedation in adults undergoing short medical procedures such as colonoscopy. Clinical data has demonstrated that remimazolam has a rapid onset and offset of action combined with a favourable cardio-respiratory safety profile.

Mr TaeHong Choi, CEO and President of Hana Pharm, said: โ€œWe are delighted to begin new partnership with Hyphens, which has expertise in gastroenterology market. By solidifying the partnership between the two companies, we will move up approval and launching period as much as possible in Singapore, and take it as a bridgehead to enter the endoscopic procedural sedation market in other Southeast Asian countries.โ€

Mr Lim See Wah, Executive Chairman and CEO of Hyphens Pharma, said: โ€œByfavoยฎ 20mg is a welcome addition to boost our specialty pharma segment. We are happy to develop and commercialise Byfavoยฎ 20mg in Singapore as it strengthens our gastroenterology portfolio that consists of brands like Vivomixxยฎ. Byfavoยฎ is a novel agent that we can offer to gastroenterologists and colorectal surgeons who perform colonoscopies. Byfavoยฎ works quickly after administration, with rapid recovery and less drowsiness and grogginess after a procedure. Its favourable safety profile helps to reduce the risk of complications and adverse events during and after a procedure.โ€

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