Drug Research

Drug development in the European pharmaceutical industry is undergoing a dramatic shift, largely due to the repurposing and reformulation of pre-existing chemicals rather than the discovery of novel molecules.   Advances in specialty intermediates, which are essential for repurposing...

The need to improve the effectiveness, safety, and accessibility of drugs drives research and innovation in the ever-evolving pharmaceutical industry.  The problem of solubility and bioavailability, which affect how well a medication reaches its intended biological target after oral...

Genmab has reported encouraging findings from the Phase 2 RAINFOL-01 trial of rinatabart sesutecan (Rina-S®), an experimental folate receptor-alpha (FRα)-targeted, TOPO1 antibody-drug combination (ADC). Data from the B1 cohort of the trial showed encouraging antitumor efficacy in highly pre-treated...

Synthetic Chemistry and Integrated Biofermentation Transformational Pharmaceutical Manufacturing Combining biofermentation with chemical synthesis is shown to be creative in the realm of pharmaceutical manufacturing.  Following industry sustainability and innovation goals, this modern approach raises manufacturing process efficiency.  Businesses, researchers, and...

LINDIS Biotech has received EMA Marketing Authorisation for catumaxomab, making it the only medicine licensed for the targeted and cancer-directed therapy of malignant ascites. Celonic Group will produce catumaxomab for commercial use. Catumaxomab will be manufactured at Celonic's...

Thermo Fisher Scientific Inc., the global leader in serving science, has announced the launch of the international CorEvitas Adolescent Alopecia Areata (AA) Registry. This initiative addresses a significant unmet need for real-world, adolescent-specific data on alopecia areata, an autoimmune...

Roche has announced that the U.S. Food and Drug Administration (FDA) has approved Susvimo® (ranibizumab injection) 100 mg/mL as the first and only continuous delivery treatment for diabetic macular edema (DME), a leading cause of vision loss in adults...