Clinical Trials - Latest News and Updates on Clinical Trials

Phase III CNS Protocol Optimization: Mitigating the Financial and Regulatory Risks of Multi-Site Imaging Scans

Yuvraj — Thu, 12 Nov 2026 07:49:36 +0000

A scan can meet a site’s routine clinical standards and still leave a trial team with an unusable assessment. Across a global imaging network, that gap creates expenses that don’t sit neatly within the imaging budget: repeat visits, reconciliation work, and unresolved questions approaching database lock. Phase III CNS Protocol Optimization brings those operational exposures […]

The post Phase III CNS Protocol Optimization: Mitigating the Financial and Regulatory Risks of Multi-Site Imaging Scans first appeared on World Pharma Today.

BioNTech and Gilead Partner for Pumitamig Clinical Trial

Yuvraj — Fri, 23 Oct 2026 13:03:30 +0000

BioNTech SE has officially entered into a clinical trial collaboration and supply agreement with Gilead Sciences Inc. to evaluate the bispecific immunomodulator pumitamig in combination with the TROP2-directed antibody-drug conjugate (ADC) sacituzumab govitecan. Announced on October 22, 2026, this strategic partnership aims to improve therapeutic outcomes for patients diagnosed with locally advanced or metastatic triple-negative […]

The post BioNTech and Gilead Partner for Pumitamig Clinical Trial first appeared on World Pharma Today.

Improving Therapeutic Development with Female Clinical Endpoints

Yuvraj — Sat, 10 Oct 2026 08:16:33 +0000

The pharmaceutical industry faces growing pressure to refine how therapeutic efficacy is measured across diverse patient populations. A significant shift in this progression involves the identification and integration of female clinical endpoints during the early and late stages of drug development. Historically, clinical research relied heavily on male-centric models, assuming that physiological responses would be […]

The post Improving Therapeutic Development with Female Clinical Endpoints first appeared on World Pharma Today.

Roche Obesity Drug Enicepatide Delivers 15.5% Weight Loss and Blood Sugar Reduction in Mid-Stage Trial

Yuvraj — Wed, 23 Sep 2026 11:26:06 +0000

Swiss pharmaceutical company Roche has announced that its experimental dual-acting obesity drug, enicepatide, helped overweight or obese patients living with type 2 diabetes achieve an average body weight reduction of 15.5% while also significantly lowering blood sugar levels in a mid-stage clinical trial. The results position Roche as a serious contender in the rapidly expanding […]

The post Roche Obesity Drug Enicepatide Delivers 15.5% Weight Loss and Blood Sugar Reduction in Mid-Stage Trial first appeared on World Pharma Today.

Clinical Trial Packaging for Investigational Product Management

Yuvraj — Mon, 14 Sep 2026 07:11:30 +0000

The management of investigational products in the pharmaceutical sector requires a high level of precision to ensure the integrity of clinical data and the safety of trial participants. This specialized packaging serves a critical role that goes far beyond the simple containment of medication. It is the primary interface between the clinical supply chain and […]

The post Clinical Trial Packaging for Investigational Product Management first appeared on World Pharma Today.

Digital Supply Chain Platforms Improving Clinical Supply Visibility

Yuvraj — Sat, 05 Sep 2026 08:14:43 +0000

The management of supplies for clinical trials has traditionally been one of the most complex and fragmented parts of the pharmaceutical product lifecycle. Unlike commercial distribution, which often follows predictable patterns, clinical logistics must handle small, patient-specific kits that move through a global network of depots and trial sites. Any disruption in this chain can […]

The post Digital Supply Chain Platforms Improving Clinical Supply Visibility first appeared on World Pharma Today.

AI-Driven Clinical Trials Are Closing the Speed Gap

Yuvraj — Sat, 27 Jun 2026 07:49:01 +0000

The pharmaceutical industry has long struggled with the bottleneck of clinical development. While the discovery of new drug candidates has accelerated through advanced computation and genomics, the process of testing these molecules in human subjects remains slow, expensive, and prone to failure. On average, it takes over a decade and billions of dollars to bring […]

The post AI-Driven Clinical Trials Are Closing the Speed Gap first appeared on World Pharma Today.

US Clinical Trials Plan Aims to Restore Research Leadership

Yuvraj — Wed, 24 Jun 2026 13:15:03 +0000

The US Department of Health and Human Services (HHS) has outlined a new strategy aimed at reinforcing the country’s position in pharmaceutical research as competition from China intensifies. Through an initiative called Operation Trailblazer, HHS plans to introduce measures designed to accelerate drug development, reduce delays in clinical studies, expand participation in research programmes, and […]

The post US Clinical Trials Plan Aims to Restore Research Leadership first appeared on World Pharma Today.

Insilico Medicine Advances ISM8969 Into Phase 1 Trial as Brain-Penetrant NLRP3 Inhibitor for Neuroinflammation

Yuvraj — Fri, 19 Jun 2026 07:39:02 +0000

Insilico Medicine has reached a significant clinical milestone with the completion of first-in-human dosing of ISM8969 in a Phase 1 study. Conducted in collaboration with Hygtia Therapeutics, the ISM8969 Phase 1 trial marks the transition of this oral, brain-penetrant NLRP3 inflammasome inhibitor from preclinical development into human evaluation. The compound is designed to address chronic […]

The post Insilico Medicine Advances ISM8969 Into Phase 1 Trial as Brain-Penetrant NLRP3 Inhibitor for Neuroinflammation first appeared on World Pharma Today.

Boehringer’s Survodutide Cuts Visceral and Liver Fat While Preserving Lean Mass in Late-Stage Trial

Yuvraj — Tue, 09 Jun 2026 07:45:56 +0000

German pharmaceutical company Boehringer Ingelheim has reported that its experimental obesity drug, survodutide, significantly reduced visceral abdominal fat and liver fat while largely preserving lean body mass in a late-stage clinical study. The data strengthens the company’s argument that the drug offers meaningful health benefits beyond overall weight loss percentage a distinction that analysts have […]

The post Boehringer’s Survodutide Cuts Visceral and Liver Fat While Preserving Lean Mass in Late-Stage Trial first appeared on World Pharma Today.